METTL14 aggravates podocyte injury and glomerulopathy progression through N 6 -methyladenosine-depen...
METTL14 aggravates podocyte injury and glomerulopathy progression through N 6 -methyladenosine-dependent downregulating of Sirt1
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Author / Creator
Lu, Zhihui , Liu, Hong , Song, Nana , Liang, Yiran , Zhu, Jiaming , Chen, Jing , Ning, Yichun , Hu, Jiachang , Fang, Yi , Teng, Jie , Zou, Jianzhou , Dai, Yan and Ding, Xiaoqiang
Publisher
England
Journal title
Language
English
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Publication information
Publisher
England
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Scope and Contents
Contents
Podocytes are known to play a determining role in the progression of proteinuric kidney disease. N
-methyladenosine (m6A), as the most abundant chemical modification in eukaryotic mRNA, has been reported to participate in various pathological processes. However, its role in podocyte injury remains unclear. In this study, we observed the elevated...
Alternative Titles
Full title
METTL14 aggravates podocyte injury and glomerulopathy progression through N 6 -methyladenosine-dependent downregulating of Sirt1
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Record Identifier
TN_cdi_pubmed_primary_34580283
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_34580283
Other Identifiers
E-ISSN
2041-4889
DOI
10.1038/s41419-021-04156-y
