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Prostaglandin D 2 metabolites activate asthmatic patient-derived type 2 innate lymphoid cells and eo...

Prostaglandin D 2 metabolites activate asthmatic patient-derived type 2 innate lymphoid cells and eo...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_34620168

Prostaglandin D 2 metabolites activate asthmatic patient-derived type 2 innate lymphoid cells and eosinophils via the DP 2 receptor

About this item

Full title

Prostaglandin D 2 metabolites activate asthmatic patient-derived type 2 innate lymphoid cells and eosinophils via the DP 2 receptor

Publisher

England

Journal title

Respiratory research, 2021-10, Vol.22 (1), p.262

Language

English

Formats

Publication information

Publisher

England

More information

Scope and Contents

Contents

Prostaglandin D
(PGD
) signaling via prostaglandin D
receptor 2 (DP
) contributes to atopic and non-atopic asthma. Inhibiting DP
has shown therapeutic benefit in certain subsets of asthma patients, improving eosinophilic airway inflammation. PGD
metabolites prolong the inflammatory response in asthmatic patients via DP
signalin...

Alternative Titles

Full title

Prostaglandin D 2 metabolites activate asthmatic patient-derived type 2 innate lymphoid cells and eosinophils via the DP 2 receptor

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_34620168

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_34620168

Other Identifiers

E-ISSN

1465-993X

DOI

10.1186/s12931-021-01852-3

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