Prostaglandin D 2 metabolites activate asthmatic patient-derived type 2 innate lymphoid cells and eo...
Prostaglandin D 2 metabolites activate asthmatic patient-derived type 2 innate lymphoid cells and eosinophils via the DP 2 receptor
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Publisher
England
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Language
English
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Publisher
England
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Contents
Prostaglandin D
(PGD
) signaling via prostaglandin D
receptor 2 (DP
) contributes to atopic and non-atopic asthma. Inhibiting DP
has shown therapeutic benefit in certain subsets of asthma patients, improving eosinophilic airway inflammation. PGD
metabolites prolong the inflammatory response in asthmatic patients via DP
signalin...
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Full title
Prostaglandin D 2 metabolites activate asthmatic patient-derived type 2 innate lymphoid cells and eosinophils via the DP 2 receptor
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TN_cdi_pubmed_primary_34620168
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_34620168
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E-ISSN
1465-993X
DOI
10.1186/s12931-021-01852-3