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Evaluation of the Inhibitory Effects of Pyridylpyrazole Derivatives on LPS-Induced PGE 2 Productions...

Evaluation of the Inhibitory Effects of Pyridylpyrazole Derivatives on LPS-Induced PGE 2 Productions...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_34770896

Evaluation of the Inhibitory Effects of Pyridylpyrazole Derivatives on LPS-Induced PGE 2 Productions and Nitric Oxide in Murine RAW 264.7 Macrophages

About this item

Full title

Evaluation of the Inhibitory Effects of Pyridylpyrazole Derivatives on LPS-Induced PGE 2 Productions and Nitric Oxide in Murine RAW 264.7 Macrophages

Publisher

Switzerland

Journal title

Molecules (Basel, Switzerland), 2021-10, Vol.26 (21)

Language

English

Formats

Publication information

Publisher

Switzerland

More information

Scope and Contents

Contents

A series of thirteen triarylpyrazole analogs were investigated as inhibitors of lipopolysaccharide (LPS)-induced prostaglandin E
(PGE
) and nitric oxide (NO) production in RAW 264.7 macrophages. The target compounds
-
have first been assessed for cytotoxicity against RAW 264.7 macrophages to determine their non-cytotoxic concentration(s...

Alternative Titles

Full title

Evaluation of the Inhibitory Effects of Pyridylpyrazole Derivatives on LPS-Induced PGE 2 Productions and Nitric Oxide in Murine RAW 264.7 Macrophages

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_34770896

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_34770896

Other Identifiers

E-ISSN

1420-3049

DOI

10.3390/molecules26216489

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