Enhanced Oral Bioavailability of Epalrestat SBE 7 -β-CD Complex Loaded Chitosan Nanoparticles: Prepa...
Enhanced Oral Bioavailability of Epalrestat SBE 7 -β-CD Complex Loaded Chitosan Nanoparticles: Preparation, Characterization and in-vivo Pharmacokinetic Evaluation
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New Zealand
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Language
English
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Publisher
New Zealand
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Contents
Epalrestat (EPL) is a carboxylic acid derivative with poor aqueous solubility and its pharmacokinetic features are not fully defined.
Current research aimed to fabricate inclusion complexation of EPL with SBE
β-CD (IC) and EPL/SBE
β-CD CS NPs (NP).
EPL was complexed with SBE
β-CD using the co-precipitation method, and the prepared co...
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Full title
Enhanced Oral Bioavailability of Epalrestat SBE 7 -β-CD Complex Loaded Chitosan Nanoparticles: Preparation, Characterization and in-vivo Pharmacokinetic Evaluation
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TN_cdi_pubmed_primary_35002232
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_35002232
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E-ISSN
1178-2013
DOI
10.2147/IJN.S339857