Relationship between astrocyte reactivity, using novel 11 C-BU99008 PET, and glucose metabolism, gre...
Relationship between astrocyte reactivity, using novel 11 C-BU99008 PET, and glucose metabolism, grey matter volume and amyloid load in cognitively impaired individuals
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Author / Creator
Livingston, Nicholas R , Calsolaro, Valeria , Hinz, Rainer , Nowell, Joseph , Raza, Sanara , Gentleman, Steve , Tyacke, Robin J , Myers, Jim , Venkataraman, Ashwin V , Perneczky, Robert , Gunn, Roger N , Rabiner, Eugenii A , Parker, Christine A , Murphy, Philip S , Wren, Paul B , Nutt, David J , Matthews, Paul M and Edison, Paul
Publisher
England
Journal title
Language
English
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Publisher
England
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Contents
Post mortem neuropathology suggests that astrocyte reactivity may play a significant role in neurodegeneration in Alzheimer's disease. We explored this in vivo using multimodal PET and MRI imaging. Twenty subjects (11 older, cognitively impaired patients and 9 age-matched healthy controls) underwent brain scanning using the novel reactive astrocyte...
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Full title
Relationship between astrocyte reactivity, using novel 11 C-BU99008 PET, and glucose metabolism, grey matter volume and amyloid load in cognitively impaired individuals
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Record Identifier
TN_cdi_pubmed_primary_35125495
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_35125495
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E-ISSN
1476-5578
DOI
10.1038/s41380-021-01429-y
