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Echinocandins - structure, mechanism of action and use in antifungal therapy

Echinocandins - structure, mechanism of action and use in antifungal therapy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_35296203

Echinocandins - structure, mechanism of action and use in antifungal therapy

About this item

Full title

Echinocandins - structure, mechanism of action and use in antifungal therapy

Publisher

England: Taylor & Francis

Journal title

Journal of enzyme inhibition and medicinal chemistry, 2022-12, Vol.37 (1), p.876-894

Language

English

Formats

Publication information

Publisher

England: Taylor & Francis

More information

Scope and Contents

Contents

With increasing number of immunocompromised patients as well as drug resistance in fungi, the risk of fatal fungal infections in humans increases as well. The action of echinocandins is based on the inhibition of β-(1,3)-d-glucan synthesis that builds the fungal cell wall. Caspofungin, micafungin, anidulafungin and rezafungin are semi-synthetic cyc...

Alternative Titles

Full title

Echinocandins - structure, mechanism of action and use in antifungal therapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_35296203

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_35296203

Other Identifiers

ISSN

1475-6366

E-ISSN

1475-6374

DOI

10.1080/14756366.2022.2050224

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