N 6 -methyladenosine-modified TRAF1 promotes sunitinib resistance by regulating apoptosis and angiog...
N 6 -methyladenosine-modified TRAF1 promotes sunitinib resistance by regulating apoptosis and angiogenesis in a METTL14-dependent manner in renal cell carcinoma
About this item
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Author / Creator
Chen, Yuanlei , Lu, Zeyi , Qi, Chao , Yu, Chenhao , Li, Yang , Huan, Wang , Wang, Ruyue , Luo, Wenqin , Shen, Danyang , Ding, Lifeng , Ren, Liangliang , Xie, Haiyun , Xue, Dingwei , Wang, Mingchao , Ni, Kangxin , Xia, Liqun , Qian, Jun and Li, Gonghui
Publisher
England
Journal title
Language
English
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Publisher
England
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Scope and Contents
Contents
Sunitinib resistance can be classified into primary and secondary resistance. While accumulating research has indicated several underlying factors contributing to sunitinib resistance, the precise mechanisms in renal cell carcinoma are still unclear.
RNA sequencing and m6A sequencing were used to screen for functional genes involved in sunitinib...
Alternative Titles
Full title
N 6 -methyladenosine-modified TRAF1 promotes sunitinib resistance by regulating apoptosis and angiogenesis in a METTL14-dependent manner in renal cell carcinoma
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmed_primary_35538475
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_35538475
Other Identifiers
E-ISSN
1476-4598
DOI
10.1186/s12943-022-01549-1
