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Regulation of APD and Force by the Na + /Ca 2+ Exchanger in Human-Induced Pluripotent Stem Cell-Deri...

Regulation of APD and Force by the Na + /Ca 2+ Exchanger in Human-Induced Pluripotent Stem Cell-Deri...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_35954268

Regulation of APD and Force by the Na + /Ca 2+ Exchanger in Human-Induced Pluripotent Stem Cell-Derived Engineered Heart Tissue

About this item

Full title

Regulation of APD and Force by the Na + /Ca 2+ Exchanger in Human-Induced Pluripotent Stem Cell-Derived Engineered Heart Tissue

Publisher

Switzerland

Journal title

Cells (Basel, Switzerland), 2022-08, Vol.11 (15)

Language

English

Formats

Publication information

Publisher

Switzerland

More information

Scope and Contents

Contents

The physiological importance of NCX in human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) is not well characterized but may depend on the relative strength of the current, compared to adult cardiomyocytes, and on the exact spatial arrangement of proteins involved in Ca2+ extrusion. Here, we determined NCX currents and its contri...

Alternative Titles

Full title

Regulation of APD and Force by the Na + /Ca 2+ Exchanger in Human-Induced Pluripotent Stem Cell-Derived Engineered Heart Tissue

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_35954268

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_35954268

Other Identifiers

E-ISSN

2073-4409

DOI

10.3390/cells11152424

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