Phase 1 study of intraventricular 131 I-omburtamab targeting B7H3 (CD276)-expressing CNS malignancie...
Phase 1 study of intraventricular 131 I-omburtamab targeting B7H3 (CD276)-expressing CNS malignancies
About this item
Full title
Author / Creator
Kramer, Kim , Pandit-Taskar, Neeta , Kushner, Brian H , Zanzonico, Pat , Humm, John L , Tomlinson, Ursula , Donzelli, Maria , Wolden, Suzanne L , Haque, Sophia , Dunkel, Ira , Souweidane, Mark M , Greenfield, Jeffrey P , Tickoo, Satish , Lewis, Jason S , Lyashchenko, Serge K , Carrasquillo, Jorge A , Chu, Bae , Horan, Christopher , Larson, Steven M , Cheung, Nai-Kong V and Modak, Shakeel
Publisher
England
Journal title
Language
English
Formats
Publication information
Publisher
England
Subjects
More information
Scope and Contents
Contents
The prognosis for metastatic and recurrent tumors of the central nervous system (CNS) remains dismal, and the need for newer therapeutic targets and modalities is critical. The cell surface glycoprotein B7H3 is expressed on a range of solid tumors with a restricted expression on normal tissues. We hypothesized that compartmental radioimmunotherapy...
Alternative Titles
Full title
Phase 1 study of intraventricular 131 I-omburtamab targeting B7H3 (CD276)-expressing CNS malignancies
Authors, Artists and Contributors
Author / Creator
Pandit-Taskar, Neeta
Kushner, Brian H
Zanzonico, Pat
Humm, John L
Tomlinson, Ursula
Donzelli, Maria
Wolden, Suzanne L
Haque, Sophia
Dunkel, Ira
Souweidane, Mark M
Greenfield, Jeffrey P
Tickoo, Satish
Lewis, Jason S
Lyashchenko, Serge K
Carrasquillo, Jorge A
Chu, Bae
Horan, Christopher
Larson, Steven M
Cheung, Nai-Kong V
Modak, Shakeel
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_36371226
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_36371226
Other Identifiers
E-ISSN
1756-8722
DOI
10.1186/s13045-022-01383-4