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Upregulation of Ca 2+ -binding proteins contributes to VTA dopamine neuron survival in the early pha...

Upregulation of Ca 2+ -binding proteins contributes to VTA dopamine neuron survival in the early pha...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_36434727

Upregulation of Ca 2+ -binding proteins contributes to VTA dopamine neuron survival in the early phases of Alzheimer's disease in Tg2576 mice

About this item

Full title

Upregulation of Ca 2+ -binding proteins contributes to VTA dopamine neuron survival in the early phases of Alzheimer's disease in Tg2576 mice

Publisher

England

Journal title

Molecular neurodegeneration, 2022-11, Vol.17 (1), p.76

Language

English

Formats

Publication information

Publisher

England

More information

Scope and Contents

Contents

Recent clinical and experimental studies have highlighted the involvement of Ventral Tegmental Area (VTA) dopamine (DA) neurons for the early pathogenesis of Alzheimer's Disease (AD). We have previously described a progressive and selective degeneration of these neurons in the Tg2576 mouse model of AD, long before amyloid-beta plaque formation. The...

Alternative Titles

Full title

Upregulation of Ca 2+ -binding proteins contributes to VTA dopamine neuron survival in the early phases of Alzheimer's disease in Tg2576 mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_36434727

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_36434727

Other Identifiers

E-ISSN

1750-1326

DOI

10.1186/s13024-022-00580-6

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