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Generation of a p21 Reporter Mouse and Its Use to Identify and Eliminate p21 high Cells In Vivo

Generation of a p21 Reporter Mouse and Its Use to Identify and Eliminate p21 high Cells In Vivo

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_36982640

Generation of a p21 Reporter Mouse and Its Use to Identify and Eliminate p21 high Cells In Vivo

About this item

Full title

Generation of a p21 Reporter Mouse and Its Use to Identify and Eliminate p21 high Cells In Vivo

Publisher

Switzerland

Journal title

International journal of molecular sciences, 2023-03, Vol.24 (6)

Language

English

Formats

Publication information

Publisher

Switzerland

More information

Scope and Contents

Contents

P21 and p16 have been identified as inducers of senescence. Many transgenic mouse models have been developed to target cells expressing high levels of
(p16
) and investigate their potential contribution to tissue dysfunction in aging, obesity, and other pathological conditions. However, the specific roles of p21 in various senescence-driven p...

Alternative Titles

Full title

Generation of a p21 Reporter Mouse and Its Use to Identify and Eliminate p21 high Cells In Vivo

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_36982640

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_36982640

Other Identifiers

E-ISSN

1422-0067

DOI

10.3390/ijms24065565

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