Generation of a p21 Reporter Mouse and Its Use to Identify and Eliminate p21 high Cells In Vivo
Generation of a p21 Reporter Mouse and Its Use to Identify and Eliminate p21 high Cells In Vivo
About this item
Full title
Author / Creator
Yi, Zimei , Ren, Le , Wei, Yu , Chen, Siyi , Zhao, Jiechen , Zhu, Jiayu and Wu, Junhua
Publisher
Switzerland
Journal title
Language
English
Formats
Publication information
Publisher
Switzerland
Subjects
More information
Scope and Contents
Contents
P21 and p16 have been identified as inducers of senescence. Many transgenic mouse models have been developed to target cells expressing high levels of
(p16
) and investigate their potential contribution to tissue dysfunction in aging, obesity, and other pathological conditions. However, the specific roles of p21 in various senescence-driven p...
Alternative Titles
Full title
Generation of a p21 Reporter Mouse and Its Use to Identify and Eliminate p21 high Cells In Vivo
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_36982640
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_36982640
Other Identifiers
E-ISSN
1422-0067
DOI
10.3390/ijms24065565