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Potential clinical implications of CD4 + CD26 high T cells for nivolumab treated melanoma patients

Potential clinical implications of CD4 + CD26 high T cells for nivolumab treated melanoma patients

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_37170241

Potential clinical implications of CD4 + CD26 high T cells for nivolumab treated melanoma patients

About this item

Full title

Potential clinical implications of CD4 + CD26 high T cells for nivolumab treated melanoma patients

Publisher

England

Journal title

Journal of translational medicine, 2023-05, Vol.21 (1), p.318

Language

English

Formats

Publication information

Publisher

England

More information

Scope and Contents

Contents

Nivolumab is an anti-PD1 antibody that has dramatically improved metastatic melanoma patients' outcomes. Nevertheless, many patients are resistant to PD-1 inhibition, occasionally experiencing severe off-target immune toxicity. In addition, no robust and reproducible biomarkers have yet been validated to identify the correct selection of patients w...

Alternative Titles

Full title

Potential clinical implications of CD4 + CD26 high T cells for nivolumab treated melanoma patients

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_37170241

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_37170241

Other Identifiers

E-ISSN

1479-5876

DOI

10.1186/s12967-023-04184-6

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