Guanidines: Synthesis of Novel Histamine H 3 R Antagonists with Additional Breast Anticancer Activit...
Guanidines: Synthesis of Novel Histamine H 3 R Antagonists with Additional Breast Anticancer Activity and Cholinesterases Inhibitory Effect
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Publisher
Switzerland
Journal title
Language
English
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Publication information
Publisher
Switzerland
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Scope and Contents
Contents
This study examines the properties of novel guanidines, designed and synthesized as histamine H
R antagonists/inverse agonists with additional pharmacological targets. We evaluated their potential against two targets viz., inhibition of MDA-MB-231, and MCF-7 breast cancer cells viability and inhibition of AChE/BuChE. ADS10310 showed micromolar c...
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Full title
Guanidines: Synthesis of Novel Histamine H 3 R Antagonists with Additional Breast Anticancer Activity and Cholinesterases Inhibitory Effect
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Record Identifier
TN_cdi_pubmed_primary_37242458
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_37242458
Other Identifiers
ISSN
1424-8247
E-ISSN
1424-8247
DOI
10.3390/ph16050675
