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EpoR Activation Stimulates Erythroid Precursor Proliferation by Inducing Phosphorylation of Tyrosine...

EpoR Activation Stimulates Erythroid Precursor Proliferation by Inducing Phosphorylation of Tyrosine...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_37443738

EpoR Activation Stimulates Erythroid Precursor Proliferation by Inducing Phosphorylation of Tyrosine-88 of the CDK-Inhibitor p27 Kip1

About this item

Full title

EpoR Activation Stimulates Erythroid Precursor Proliferation by Inducing Phosphorylation of Tyrosine-88 of the CDK-Inhibitor p27 Kip1

Publisher

Switzerland

Journal title

Cells (Basel, Switzerland), 2023-06, Vol.12 (13)

Language

English

Formats

Publication information

Publisher

Switzerland

More information

Scope and Contents

Contents

Erythrocyte biogenesis needs to be tightly regulated to secure oxygen transport and control plasma viscosity. The cytokine erythropoietin (Epo) governs erythropoiesis by promoting cell proliferation, differentiation, and survival of erythroid precursor cells. Erythroid differentiation is associated with an accumulation of the cyclin-dependent kinas...

Alternative Titles

Full title

EpoR Activation Stimulates Erythroid Precursor Proliferation by Inducing Phosphorylation of Tyrosine-88 of the CDK-Inhibitor p27 Kip1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_37443738

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_37443738

Other Identifiers

E-ISSN

2073-4409

DOI

10.3390/cells12131704

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