Selection of cross-reactive T cells by commensal and food-derived yeasts drives cytotoxic T H 1 cell...
Selection of cross-reactive T cells by commensal and food-derived yeasts drives cytotoxic T H 1 cell responses in Crohn's disease
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Martini, Gabriela Rios , Tikhonova, Ekaterina , Rosati, Elisa , DeCelie, Meghan Bialt , Sievers, Laura Katharina , Tran, Florian , Lessing, Matthias , Bergfeld, Arne , Hinz, Sophia , Nikolaus, Susanna , Kümpers, Julia , Matysiak, Anna , Hofmann, Philipp , Saggau, Carina , Schneiders, Stephan , Kamps, Ann-Kristin , Jacobs, Gunnar , Lieb, Wolfgang , Maul, Jochen , Siegmund, Britta , Seegers, Barbara , Hinrichsen, Holger , Oberg, Hans-Heinrich , Wesch, Daniela , Bereswill, Stefan , Heimesaat, Markus M , Rupp, Jan , Kniemeyer, Olaf , Brakhage, Axel A , Brunke, Sascha , Hube, Bernhard , Aden, Konrad , Franke, Andre , Iliev, Iliyan D , Scheffold, Alexander , Schreiber, Stefan and Bacher, Petra
Publisher
United States
Journal title
Language
English
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Publisher
United States
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Contents
Aberrant CD4
T cell reactivity against intestinal microorganisms is considered to drive mucosal inflammation in inflammatory bowel diseases. The disease-relevant microbial species and the corresponding microorganism-specific, pathogenic T cell phenotypes remain largely unknown. In the present study, we identified common gut commensal and food-de...
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Full title
Selection of cross-reactive T cells by commensal and food-derived yeasts drives cytotoxic T H 1 cell responses in Crohn's disease
Authors, Artists and Contributors
Author / Creator
Tikhonova, Ekaterina
Rosati, Elisa
DeCelie, Meghan Bialt
Sievers, Laura Katharina
Tran, Florian
Lessing, Matthias
Bergfeld, Arne
Hinz, Sophia
Nikolaus, Susanna
Kümpers, Julia
Matysiak, Anna
Hofmann, Philipp
Saggau, Carina
Schneiders, Stephan
Kamps, Ann-Kristin
Jacobs, Gunnar
Lieb, Wolfgang
Maul, Jochen
Siegmund, Britta
Seegers, Barbara
Hinrichsen, Holger
Oberg, Hans-Heinrich
Wesch, Daniela
Bereswill, Stefan
Heimesaat, Markus M
Rupp, Jan
Kniemeyer, Olaf
Brakhage, Axel A
Brunke, Sascha
Hube, Bernhard
Aden, Konrad
Franke, Andre
Iliev, Iliyan D
Scheffold, Alexander
Schreiber, Stefan
Bacher, Petra
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Record Identifier
TN_cdi_pubmed_primary_37749331
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_37749331
Other Identifiers
E-ISSN
1546-170X
DOI
10.1038/s41591-023-02556-5