Structural insights into the agonists binding and receptor selectivity of human histamine H 4 recept...
Structural insights into the agonists binding and receptor selectivity of human histamine H 4 receptor
About this item
Full title
Structural insights into the agonists binding and receptor selectivity of human histamine H 4 receptor
Author / Creator
Publisher
England
Journal title
Nature communications, 2023-10, Vol.14 (1), p.6538
Language
English
Formats
Publication information
Publisher
England
Subjects
More information
Scope and Contents
Contents
Histamine is a biogenic amine that participates in allergic and inflammatory processes by stimulating histamine receptors. The histamine H
receptor (H
R) is a potential therapeutic target for chronic inflammatory diseases such as asthma and atopic dermatitis. Here, we show the cryo-electron microscopy structures of the H
R-G
complex bou...
Alternative Titles
Full title
Structural insights into the agonists binding and receptor selectivity of human histamine H 4 receptor
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_37863901
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_37863901
Other Identifiers
E-ISSN
2041-1723
DOI
10.1038/s41467-023-42260-z
