Rational Design, Synthesis, and Anti-Proliferative Evaluation of Novel 4-Aryl-3,4-Dihydro-2 H -1,4-B...
Rational Design, Synthesis, and Anti-Proliferative Evaluation of Novel 4-Aryl-3,4-Dihydro-2 H -1,4-Benzoxazines
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Switzerland
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Language
English
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Switzerland
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A synthetic pathway to a novel 4-aryl-3,4-dihydro-2
-1,4-benzoxazine scaffold was developed and a series of compounds based on the scaffold were synthesised as potential anticancer agents. The 4-aryl-substituted compounds were prepared via Buchwald-Hartwig cross-coupling between substituted bromobenzenes and various 1,4-benzoxazines, which in tu...
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Full title
Rational Design, Synthesis, and Anti-Proliferative Evaluation of Novel 4-Aryl-3,4-Dihydro-2 H -1,4-Benzoxazines
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TN_cdi_pubmed_primary_38202749
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_38202749
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E-ISSN
1420-3049
DOI
10.3390/molecules29010166