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Peroxiredoxin 1 inhibits streptozotocin-induced Alzheimer's disease-like pathology in hippocampal ne...

Peroxiredoxin 1 inhibits streptozotocin-induced Alzheimer's disease-like pathology in hippocampal ne...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_38977865

Peroxiredoxin 1 inhibits streptozotocin-induced Alzheimer's disease-like pathology in hippocampal neuronal cells via the blocking of Ca 2+ /Calpain/Cdk5-mediated mitochondrial fragmentation

About this item

Full title

Peroxiredoxin 1 inhibits streptozotocin-induced Alzheimer's disease-like pathology in hippocampal neuronal cells via the blocking of Ca 2+ /Calpain/Cdk5-mediated mitochondrial fragmentation

Publisher

England

Journal title

Scientific reports, 2024-07, Vol.14 (1), p.15642

Language

English

Formats

Publication information

Publisher

England

More information

Scope and Contents

Contents

Oxidative stress plays an essential role in the progression of Alzheimer's disease (AD), the most common age-related neurodegenerative disorder. Streptozotocin (STZ)-induced abnormal brain insulin signaling and oxidative stress play crucial roles in the progression of Alzheimer's disease (AD)-like pathology. Peroxiredoxins (Prxs) are associated wit...

Alternative Titles

Full title

Peroxiredoxin 1 inhibits streptozotocin-induced Alzheimer's disease-like pathology in hippocampal neuronal cells via the blocking of Ca 2+ /Calpain/Cdk5-mediated mitochondrial fragmentation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_38977865

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_38977865

Other Identifiers

E-ISSN

2045-2322

DOI

10.1038/s41598-024-66256-x

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