RhoA-mediated G 12 -G 13 signaling maintains muscle stem cell quiescence and prevents stem cell loss
RhoA-mediated G 12 -G 13 signaling maintains muscle stem cell quiescence and prevents stem cell loss
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England
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Language
English
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England
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Multiple processes control quiescence of muscle stem cells (MuSCs), which is instrumental to guarantee long-term replenishment of the stem cell pool. Here, we describe that the G-proteins G
-G
integrate signals from different G-protein-coupled receptors (GPCRs) to control MuSC quiescence via activation of RhoA. Comprehensive screening of GPCR...
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Full title
RhoA-mediated G 12 -G 13 signaling maintains muscle stem cell quiescence and prevents stem cell loss
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TN_cdi_pubmed_primary_39009565
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_39009565
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ISSN
2056-5968
E-ISSN
2056-5968
DOI
10.1038/s41421-024-00696-7