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Loss of Lkb1 cooperates with Braf V600E and ultraviolet radiation, increasing melanoma multiplicity...

Loss of Lkb1 cooperates with Braf V600E and ultraviolet radiation, increasing melanoma multiplicity...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_39115053

Loss of Lkb1 cooperates with Braf V600E and ultraviolet radiation, increasing melanoma multiplicity and neural‐like dedifferentiation

About this item

Full title

Loss of Lkb1 cooperates with Braf V600E and ultraviolet radiation, increasing melanoma multiplicity and neural‐like dedifferentiation

Publisher

United States

Journal title

Molecular oncology, 2025-02, Vol.19 (2), p.329-343

Language

English

Formats

Publication information

Publisher

United States

More information

Scope and Contents

Contents

The mechanisms that work alongside
BRAF
V600E
oncogene in melanoma development, in addition to ultraviolet (UV) radiation (UVR), are of great interest. Analysis of human melanoma tumors [data from The Cancer Genome Atlas (TCGA)] revealed that 50% or more of the samples expressed no or low amounts of serine/threonine protein kinase STK11 (a...

Alternative Titles

Full title

Loss of Lkb1 cooperates with Braf V600E and ultraviolet radiation, increasing melanoma multiplicity and neural‐like dedifferentiation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_39115053

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_39115053

Other Identifiers

ISSN

1574-7891

E-ISSN

1878-0261

DOI

10.1002/1878-0261.13715

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