Preparation and Preclinical Evaluation of 18 F-Labeled Olutasidenib Derivatives for Non-Invasive Det...
Preparation and Preclinical Evaluation of 18 F-Labeled Olutasidenib Derivatives for Non-Invasive Detection of Mutated Isocitrate Dehydrogenase 1 (mIDH1)
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Switzerland
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English
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Switzerland
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Mutations of isocitrate dehydrogenase 1 (IDH1) are key biomarkers for glioma classification, but current methods for detection of mutated IDH1 (mIDH1) require invasive tissue sampling and cannot be used for longitudinal studies. Positron emission tomography (PET) imaging with mIDH1-selective radioligands is a promising alternative approach that cou...
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Preparation and Preclinical Evaluation of 18 F-Labeled Olutasidenib Derivatives for Non-Invasive Detection of Mutated Isocitrate Dehydrogenase 1 (mIDH1)
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TN_cdi_pubmed_primary_39203017
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_39203017
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E-ISSN
1420-3049
DOI
10.3390/molecules29163939
