Basic Science and Pathogenesis
Basic Science and Pathogenesis
About this item
Full title
Basic Science and Pathogenesis
Author / Creator
Publisher
United States
Journal title
Alzheimer's & dementia, 2024-12, Vol.20 Suppl 1, p.e092571
Language
English
Formats
Publication information
Publisher
United States
Subjects
More information
Scope and Contents
Contents
Apolipoprotein E (ApoE) exhibits isoform-specific interactions with Alzheimer's disease (AD)-related pathology. In comparison with the more common ApoE3 isoform, ApoE4 promotes amyloid-β (Aβ) deposition, enhances tau-mediated neurodegeneration and inflammation. However, the lack of appropriate preclinical models has limited the ability to evaluate...
Alternative Titles
Full title
Basic Science and Pathogenesis
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_39751296
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_39751296
Other Identifiers
E-ISSN
1552-5279
DOI
10.1002/alz.092571
