Divergent roles of m 6 A in orchestrating brown and white adipocyte transcriptomes and systemic meta...
Divergent roles of m 6 A in orchestrating brown and white adipocyte transcriptomes and systemic metabolism
About this item
Full title
Divergent roles of m 6 A in orchestrating brown and white adipocyte transcriptomes and systemic metabolism
Author / Creator
Publisher
England
Journal title
Nature communications, 2025-01, Vol.16 (1), p.533
Language
English
Formats
Publication information
Publisher
England
Subjects
More information
Scope and Contents
Contents
N
-methyladenosine (m
A) is among the most abundant mRNA modifications, yet its cell-type-specific regulatory roles remain unclear. Here we show that m
A methyltransferase-like 14 (METTL14) differentially regulates transcriptome in brown versus white adipose tissue (BAT and WAT), leading to divergent metabolic outcomes. In humans and mice...
Alternative Titles
Full title
Divergent roles of m 6 A in orchestrating brown and white adipocyte transcriptomes and systemic metabolism
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_39788955
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_39788955
Other Identifiers
E-ISSN
2041-1723
DOI
10.1038/s41467-024-55694-w
