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Synthesis and in vitro evaluation of spirobenzovesamicols as potential 11 C-PET tracer alternatives...

Synthesis and in vitro evaluation of spirobenzovesamicols as potential 11 C-PET tracer alternatives...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_39894871

Synthesis and in vitro evaluation of spirobenzovesamicols as potential 11 C-PET tracer alternatives to [ 18 F]FEOBV for vesicular acetylcholine transporter (VAChT) imaging

About this item

Full title

Synthesis and in vitro evaluation of spirobenzovesamicols as potential 11 C-PET tracer alternatives to [ 18 F]FEOBV for vesicular acetylcholine transporter (VAChT) imaging

Publisher

England

Journal title

EJNMMI radiopharmacy and chemistry, 2025-02, Vol.10 (1), p.7

Language

English

Formats

Publication information

Publisher

England

More information

Scope and Contents

Contents

Through its central role in neurotransmission, the vesicular acetylcholine transporter (VAChT) is an increasingly valuable target for positron emission tomography (PET). VAChT ligands have been mostly derived from the vesamicol structure, but with limitations in available labelling methods and selectivity for VAChT against σ receptors being a commo...

Alternative Titles

Full title

Synthesis and in vitro evaluation of spirobenzovesamicols as potential 11 C-PET tracer alternatives to [ 18 F]FEOBV for vesicular acetylcholine transporter (VAChT) imaging

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_39894871

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_39894871

Other Identifiers

E-ISSN

2365-421X

DOI

10.1186/s41181-025-00327-w

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