Induction of Vascular Endothelial Growth Factor Expression by Hypoxia and by glucose Deficiency in M...
Induction of Vascular Endothelial Growth Factor Expression by Hypoxia and by glucose Deficiency in Multicell Spheroids: Implications for Tumor Angiogenesis
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United States: The National Academy of Sciences of the United States
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English
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United States: The National Academy of Sciences of the United States
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Perfusion insufficiency, and the resultant hypoxia, often induces a compensatory neovascularization to satisfy the needs of the tissue. We have used multicellular tumor spheroids, simulating avascular microenvironments within a clonal population of glioma tumor cells, in conjunction with in- situ analysis of gene expression, to study stress inducib...
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Full title
Induction of Vascular Endothelial Growth Factor Expression by Hypoxia and by glucose Deficiency in Multicell Spheroids: Implications for Tumor Angiogenesis
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TN_cdi_pubmed_primary_7531342
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_7531342
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.92.3.768
