Macrophage Foam Cells from Experimental Atheroma Constitutively Produce Matrix-Degrading Proteinases
Macrophage Foam Cells from Experimental Atheroma Constitutively Produce Matrix-Degrading Proteinases
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Publisher
United States: National Academy of Sciences of the United States of America
Journal title
Language
English
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Publisher
United States: National Academy of Sciences of the United States of America
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Scope and Contents
Contents
Monocyte-derived foam cells figure prominently in rupture-prone regions of atherosclerotic plaques. Peripheral blood monocytes in culture can produce certain enzymes that degrade extracellular matrix, known as matrix metalloproteinases (MMPs). Lipid-laden macrophages may thus contribute to weakening of extracellular matrix of rupture-prone atherosc...
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Full title
Macrophage Foam Cells from Experimental Atheroma Constitutively Produce Matrix-Degrading Proteinases
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Author / Creator
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Record Identifier
TN_cdi_pubmed_primary_7831299
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_7831299
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.92.2.402
