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Genetic Analysis of the Multidrug Transporter

Genetic Analysis of the Multidrug Transporter

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_8825488

Genetic Analysis of the Multidrug Transporter

About this item

Full title

Genetic Analysis of the Multidrug Transporter

Publisher

Palo Alto, CA 94303-0139: Annual Reviews

Journal title

Annual review of genetics, 1995-01, Vol.29 (1), p.607-649

Language

English

Formats

Publication information

Publisher

Palo Alto, CA 94303-0139: Annual Reviews

More information

Scope and Contents

Contents

The analysis of how human cancers evade chemotherapy has revealed a rich variety of cell-based genetic changes resulting in drug resistance. One of the best studied of these genetic alterations is increased expression of an ATP-dependent plasma membrane transport system, known as P-glycoprotein, or the multidrug transporter. This transporter active...

Alternative Titles

Full title

Genetic Analysis of the Multidrug Transporter

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_8825488

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_8825488

Other Identifiers

ISSN

0066-4197

E-ISSN

1545-2948

DOI

10.1146/annurev.ge.29.120195.003135

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