Genetic Analysis of the Multidrug Transporter
Genetic Analysis of the Multidrug Transporter
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Publisher
Palo Alto, CA 94303-0139: Annual Reviews
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Language
English
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Publisher
Palo Alto, CA 94303-0139: Annual Reviews
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Contents
The analysis of how human cancers evade chemotherapy has revealed a rich variety of cell-based genetic changes resulting in drug resistance. One of the best studied of these genetic alterations is increased expression of an ATP-dependent plasma membrane transport system, known as P-glycoprotein, or the multidrug transporter. This transporter active...
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Full title
Genetic Analysis of the Multidrug Transporter
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Record Identifier
TN_cdi_pubmed_primary_8825488
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_8825488
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ISSN
0066-4197
E-ISSN
1545-2948
DOI
10.1146/annurev.ge.29.120195.003135