Molecular Determinants of Tissue Selectivity in Estrogen Receptor Modulators
Molecular Determinants of Tissue Selectivity in Estrogen Receptor Modulators
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Publisher
United States: National Academy of Sciences of the United States of America
Journal title
Language
English
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Publication information
Publisher
United States: National Academy of Sciences of the United States of America
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Contents
Interaction of the estrogen receptor/ligand complex with a DNA estrogen response element is known to regulate gene transcription. In turn, specific conformations of the receptor-ligand complex have been postulated to influence unique subsets of estrogen-responsive genes resulting in differential modulation and, ultimately, tissue-selective outcomes...
Alternative Titles
Full title
Molecular Determinants of Tissue Selectivity in Estrogen Receptor Modulators
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Record Identifier
TN_cdi_pubmed_primary_9391160
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_9391160
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.94.25.14105
