Yeast cells expressing differential levels of human or yeast DNA topoisomerase II: a potent tool for...
Yeast cells expressing differential levels of human or yeast DNA topoisomerase II: a potent tool for identification and characterization of topoisomerase II-targeting antitumour agents
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Publisher
Berlin: Springer
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Language
English
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Publisher
Berlin: Springer
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Scope and Contents
Contents
To identify and characterize the specificity and potency of topoisomerase II-interacting antitumour drugs in an in vivo model utilizing the yeast Saccharomyces cerevisiae.
Four yeast transformants were selected for the expression of either human or yeast DNA topoisomerase II at different, biologically relevant, levels under the tight control of...
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Full title
Yeast cells expressing differential levels of human or yeast DNA topoisomerase II: a potent tool for identification and characterization of topoisomerase II-targeting antitumour agents
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Author / Creator
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Record Identifier
TN_cdi_pubmed_primary_9771947
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_9771947
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ISSN
0344-5704
E-ISSN
1432-0843
DOI
10.1007/s002800050828
