Obesity and Mild Hyperinsulinemia Found in Neuropeptide Y-Y1 Receptor-Deficient Mice
Obesity and Mild Hyperinsulinemia Found in Neuropeptide Y-Y1 Receptor-Deficient Mice
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United States: National Academy of Sciences of the United States of America
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Language
English
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Publisher
United States: National Academy of Sciences of the United States of America
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Contents
To elucidate the role of neuropeptide Y (NPY)-Y1 receptor (Y1-R) in food intake, energy expenditure, and other possible functions, we have generated Y1-R-deficient mice (Y1-R-/-) by gene targeting. Contrary to our hypothesis that the lack of NPY signaling via Y1-R would result in impaired feeding and weight loss, Y1-R-/-mice showed a moderate obesi...
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Full title
Obesity and Mild Hyperinsulinemia Found in Neuropeptide Y-Y1 Receptor-Deficient Mice
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TN_cdi_pubmed_primary_9861026
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_9861026
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.95.26.15659
