Mitochondrial DNA variation in Alzheimer’s disease reveals a unique microprotein called SHMOOSE
Mitochondrial DNA variation in Alzheimer’s disease reveals a unique microprotein called SHMOOSE
About this item
Full title
Author / Creator
Miller, Brendan , Kim, Su-Jeong , Mehta, Hemal H. , Cao, Kevin , Kumagai, Hiroshi , Thumaty, Neehar , Leelaprachakul, Naphada , Braniff, Regina Gonzalez , Jiao, Henry , Vaughan, Joan , Diedrich, Jolene , Saghatelian, Alan , Arpawong, Thalida E. , Crimmins, Eileen M. , Ertekin-Taner, Nilüfer , Tubi, Meral A. , Hare, Evan T. , Braskie, Meredith N. , Décarie-Spain, Léa , Kanoski, Scott E. , Grodstein, Francine , Bennett, David A. , Zhao, Lu , Toga, Arthur W. , Wan, Junxiang , Yen, Kelvin , Cohen, Pinchas , for the Alzheimer’s Disease Neuroimaging Initiative and Alzheimer’s Disease Neuroimaging Initiative
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Mitochondrial DNA variants have previously associated with disease, but the underlying mechanisms have been largely elusive. Here, we report that mitochondrial SNP rs2853499 associated with Alzheimer’s disease (AD), neuroimaging, and transcriptomics. We mapped rs2853499 to a novel mitochondrial small open reading frame called SHMOOSE with microprot...
Alternative Titles
Full title
Mitochondrial DNA variation in Alzheimer’s disease reveals a unique microprotein called SHMOOSE
Authors, Artists and Contributors
Author / Creator
Kim, Su-Jeong
Mehta, Hemal H.
Cao, Kevin
Kumagai, Hiroshi
Thumaty, Neehar
Leelaprachakul, Naphada
Braniff, Regina Gonzalez
Jiao, Henry
Vaughan, Joan
Diedrich, Jolene
Saghatelian, Alan
Arpawong, Thalida E.
Crimmins, Eileen M.
Ertekin-Taner, Nilüfer
Tubi, Meral A.
Hare, Evan T.
Braskie, Meredith N.
Décarie-Spain, Léa
Kanoski, Scott E.
Grodstein, Francine
Bennett, David A.
Zhao, Lu
Toga, Arthur W.
Wan, Junxiang
Yen, Kelvin
Cohen, Pinchas
for the Alzheimer’s Disease Neuroimaging Initiative
Alzheimer’s Disease Neuroimaging Initiative
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10027624
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10027624
Other Identifiers
ISSN
1359-4184,1476-5578
E-ISSN
1476-5578
DOI
10.1038/s41380-022-01769-3
