Subcellular Epithelial HMGB1 Expression Is Associated with Colorectal Neoplastic Progression, Male S...
Subcellular Epithelial HMGB1 Expression Is Associated with Colorectal Neoplastic Progression, Male Sex, Mismatch Repair Protein Expression, Lymph Node Positivity, and an 'Immune Cold' Phenotype Associated with Poor Survival
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Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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New treatment targets are needed for colorectal cancer (CRC). We define expression of High Mobility Group Box 1 (HMGB1) protein throughout colorectal neoplastic progression and examine the biological consequences of aberrant expression. HMGB1 is a ubiquitously expressed nuclear protein that shuttles to the cytoplasm under cellular stress. HMGB1 imp...
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Full title
Subcellular Epithelial HMGB1 Expression Is Associated with Colorectal Neoplastic Progression, Male Sex, Mismatch Repair Protein Expression, Lymph Node Positivity, and an 'Immune Cold' Phenotype Associated with Poor Survival
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10047220
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10047220
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ISSN
2072-6694
E-ISSN
2072-6694
DOI
10.3390/cancers15061865
