Effects of Human LAV-BPIFB4 Gene Therapy on the Epigenetic Clock and Health of Aged Mice
Effects of Human LAV-BPIFB4 Gene Therapy on the Epigenetic Clock and Health of Aged Mice
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Author / Creator
Giuliani, Maria Elisa , Barbi, Veronica , Bigossi, Giorgia , Marcozzi, Serena , Giacconi, Robertina , Cardelli, Maurizio , Piacenza, Francesco , Orlando, Fiorenza , Ciaglia, Elena , Cattaneo, Monica , Mongelli, Alessia , Gaetano, Carlo , Provinciali, Mauro , Puca, Annibale Alessandro and Malavolta, Marco
Publisher
Switzerland: MDPI AG
Journal title
Language
English
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Publisher
Switzerland: MDPI AG
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Scope and Contents
Contents
The homozygous genotype of the Longevity-Associated Variant (LAV) in Bactericidal/Permeability-Increasing Fold-Containing Family B member 4 (BPIFB4) is enriched in long-living individuals of three independent populations and its genetic transfer in C57BL/6J mice showed a delay in frailty progression and improvement of several biomarkers of aging an...
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Full title
Effects of Human LAV-BPIFB4 Gene Therapy on the Epigenetic Clock and Health of Aged Mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10095240
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10095240
Other Identifiers
ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms24076464
