Metformin Attenuates Tau Pathology in Tau-Seeded PS19 Mice
Metformin Attenuates Tau Pathology in Tau-Seeded PS19 Mice
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Author / Creator
Zhao, Shuai , Fan, Ziqi , Zhang, Xinyi , Li, Zheyu , Shen, Ting , Li, Kaicheng , Yan, Yaping , Yuan, Yunfeng , Pu, Jiali , Tian, Jun , Liu, Zhirong , Chen, Yanxing and Zhang, Baorong
Publisher
Cham: Springer International Publishing
Journal title
Language
English
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Publisher
Cham: Springer International Publishing
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Scope and Contents
Contents
Accumulation of neurofibrillary tangles (NFTs) composed of hyperphosphorylated tau is a histopathological hallmark of Alzheimer’s disease (AD) and related tauopathies. Growing evidence demonstrated that tau pathology in AD spreads in a prion-like manner. Previous studies showed that metformin might have a positive effect on cognition. However, the...
Alternative Titles
Full title
Metformin Attenuates Tau Pathology in Tau-Seeded PS19 Mice
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10121992
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10121992
Other Identifiers
ISSN
1933-7213,1878-7479
E-ISSN
1878-7479
DOI
10.1007/s13311-022-01316-6
