Selective inhibition of HDAC6 promotes bladder cancer radiosensitization and mitigates the radiation...
Selective inhibition of HDAC6 promotes bladder cancer radiosensitization and mitigates the radiation-induced CXCL1 signalling
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Background
Although trimodality therapy resecting tumours followed by chemoradiotherapy is emerged for muscle-invasive bladder cancer (MIBC), chemotherapy produces toxicities. Histone deacetylase inhibitors have been identified as an effective strategy to enhance cancer radiotherapy (RT).
Methods
We examined the role of HDAC6 and specific...
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Full title
Selective inhibition of HDAC6 promotes bladder cancer radiosensitization and mitigates the radiation-induced CXCL1 signalling
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10133394
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10133394
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ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/s41416-023-02195-0