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Early and extensive alterations of glial connexins, distal oligodendrogliopathy type demyelination,...

Early and extensive alterations of glial connexins, distal oligodendrogliopathy type demyelination,...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10154368

Early and extensive alterations of glial connexins, distal oligodendrogliopathy type demyelination, and nodal/paranodal pathology are characteristic of multiple system atrophy

About this item

Full title

Early and extensive alterations of glial connexins, distal oligodendrogliopathy type demyelination, and nodal/paranodal pathology are characteristic of multiple system atrophy

Publisher

Switzerland: John Wiley & Sons, Inc

Journal title

Brain pathology (Zurich, Switzerland), 2023-05, Vol.33 (3), p.e13131-n/a

Language

English

Formats

Publication information

Publisher

Switzerland: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

The pathological hallmark of multiple system atrophy (MSA) is aberrant accumulation of phosphorylated α‐synuclein in oligodendrocytes, forming glial cytoplasmic inclusions (GCIs). Extensive demyelination occurs particularly in the olivopontocerebellar and striatonigral pathways, but its precise mechanism remains elusive. Glial connexins (Cxs), whic...

Alternative Titles

Full title

Early and extensive alterations of glial connexins, distal oligodendrogliopathy type demyelination, and nodal/paranodal pathology are characteristic of multiple system atrophy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10154368

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10154368

Other Identifiers

ISSN

1015-6305

E-ISSN

1750-3639

DOI

10.1111/bpa.13131

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