Early and extensive alterations of glial connexins, distal oligodendrogliopathy type demyelination,...
Early and extensive alterations of glial connexins, distal oligodendrogliopathy type demyelination, and nodal/paranodal pathology are characteristic of multiple system atrophy
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Publisher
Switzerland: John Wiley & Sons, Inc
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Language
English
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Publisher
Switzerland: John Wiley & Sons, Inc
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Contents
The pathological hallmark of multiple system atrophy (MSA) is aberrant accumulation of phosphorylated α‐synuclein in oligodendrocytes, forming glial cytoplasmic inclusions (GCIs). Extensive demyelination occurs particularly in the olivopontocerebellar and striatonigral pathways, but its precise mechanism remains elusive. Glial connexins (Cxs), whic...
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Full title
Early and extensive alterations of glial connexins, distal oligodendrogliopathy type demyelination, and nodal/paranodal pathology are characteristic of multiple system atrophy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10154368
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10154368
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ISSN
1015-6305
E-ISSN
1750-3639
DOI
10.1111/bpa.13131