Pharmacokinetic and dose‐finding study of osimertinib in patients with impaired renal function and l...
Pharmacokinetic and dose‐finding study of osimertinib in patients with impaired renal function and low body weight
About this item
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Author / Creator
Fujiwara, Yutaka , Makihara, Reiko , Hase, Tetsunari , Hashimoto, Naozumi , Naito, Tomoyuki , Tsubata, Yukari , Okuno, Takae , Takahashi, Toshiaki , Kobayashi, Haruki , Shinno, Yuki , Zenke, Yoshitaka , Ikeda, Takaya , Hosomi, Yukio , Watanabe, Kageaki , Kitazono, Satoru , Sakiyama, Naomi , Makino, Yoshinori and Yamamoto, Noboru
Publisher
England: John Wiley & Sons, Inc
Journal title
Language
English
Formats
Publication information
Publisher
England: John Wiley & Sons, Inc
Subjects
More information
Scope and Contents
Contents
The safety of osimertinib is limited in patients with severe or moderate renal impairment, or low body weight. This study aimed to investigate the safety, pharmacokinetics (PK) and recommended dose (RD) of osimertinib in patients with epidermal growth factor receptor (EGFR)‐mutated non–small cell lung cancer (NSCLC) with impaired renal function and...
Alternative Titles
Full title
Pharmacokinetic and dose‐finding study of osimertinib in patients with impaired renal function and low body weight
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10154887
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10154887
Other Identifiers
ISSN
1347-9032
E-ISSN
1349-7006
DOI
10.1111/cas.15736
