Altered neuronal activity in the ventromedial prefrontal cortex drives nicotine intake escalation
Altered neuronal activity in the ventromedial prefrontal cortex drives nicotine intake escalation
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Publisher
England: Nature Publishing Group
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Language
English
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Publisher
England: Nature Publishing Group
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Contents
Nicotine addiction develops after prolonged drug use and escalation of drug intake. However, because of difficulties in demonstrating escalation of nicotine use in rats, its underlying neuroadaptations still remain poorly understood. Here we report that access to unusually high doses of nicotine (i.e., from 30 µg to 240 µg/kg/injection) for self-ad...
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Full title
Altered neuronal activity in the ventromedial prefrontal cortex drives nicotine intake escalation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10156690
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10156690
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ISSN
0893-133X
E-ISSN
1740-634X,0007-0920
DOI
10.1038/s41386-022-01428-9
