Gli1 promotes the phenotypic transformation of valve interstitial cells through Hedgehog pathway act...
Gli1 promotes the phenotypic transformation of valve interstitial cells through Hedgehog pathway activation exacerbating calcific aortic valve disease
About this item
Full title
Author / Creator
Huang, Yuming , Jiang, Chen , Chen, Liang , Han, Juanjuan , Liu, Ming , Zhou, Tingwen , Dong, Nianguo and Xu, Kang
Publisher
Australia: Ivyspring International Publisher
Journal title
Language
English
Formats
Publication information
Publisher
Australia: Ivyspring International Publisher
Subjects
More information
Scope and Contents
Contents
Calcific aortic valve disease (CAVD) is the most prevalent human valve disease worldwide. Multiple factors induce "irreversible" pathological changes in the aortic valve leaflets, resulting in changes in cardiac hemodynamics, eventually leading to heart failure. However, no effective pharmaceutical interventions have been found and prosthetic valve...
Alternative Titles
Full title
Gli1 promotes the phenotypic transformation of valve interstitial cells through Hedgehog pathway activation exacerbating calcific aortic valve disease
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10158026
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10158026
Other Identifiers
ISSN
1449-2288
E-ISSN
1449-2288
DOI
10.7150/ijbs.74123