Log in to save to my catalogue

Gli1 promotes the phenotypic transformation of valve interstitial cells through Hedgehog pathway act...

Gli1 promotes the phenotypic transformation of valve interstitial cells through Hedgehog pathway act...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10158026

Gli1 promotes the phenotypic transformation of valve interstitial cells through Hedgehog pathway activation exacerbating calcific aortic valve disease

About this item

Full title

Gli1 promotes the phenotypic transformation of valve interstitial cells through Hedgehog pathway activation exacerbating calcific aortic valve disease

Publisher

Australia: Ivyspring International Publisher

Journal title

International journal of biological sciences, 2023-01, Vol.19 (7), p.2053-2066

Language

English

Formats

Publication information

Publisher

Australia: Ivyspring International Publisher

More information

Scope and Contents

Contents

Calcific aortic valve disease (CAVD) is the most prevalent human valve disease worldwide. Multiple factors induce "irreversible" pathological changes in the aortic valve leaflets, resulting in changes in cardiac hemodynamics, eventually leading to heart failure. However, no effective pharmaceutical interventions have been found and prosthetic valve...

Alternative Titles

Full title

Gli1 promotes the phenotypic transformation of valve interstitial cells through Hedgehog pathway activation exacerbating calcific aortic valve disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10158026

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10158026

Other Identifiers

ISSN

1449-2288

E-ISSN

1449-2288

DOI

10.7150/ijbs.74123

How to access this item