F-actin–rich territories coordinate apoptosome assembly and caspase activation during DNA damage–ind...
F-actin–rich territories coordinate apoptosome assembly and caspase activation during DNA damage–induced intrinsic apoptosis
About this item
Full title
Author / Creator
Publisher
United States: The American Society for Cell Biology
Journal title
Language
English
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Publication information
Publisher
United States: The American Society for Cell Biology
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More information
Scope and Contents
Contents
DNA damage–induced apoptosis relies on signaling platforms called apoptosomes and the activation of caspase proteases, but how their activities are coordinated in cells is not well understood. The cytoskeleton assembles into an F-actin–rich territory that couples the apoptosome biogenesis process to the initiation of caspase activation.
The acti...
Alternative Titles
Full title
F-actin–rich territories coordinate apoptosome assembly and caspase activation during DNA damage–induced intrinsic apoptosis
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10162420
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10162420
Other Identifiers
ISSN
1059-1524
E-ISSN
1939-4586
DOI
10.1091/mbc.E22-04-0119
