Immune correlates analysis of the ENSEMBLE single Ad26.COV2.S dose vaccine efficacy clinical trial
Immune correlates analysis of the ENSEMBLE single Ad26.COV2.S dose vaccine efficacy clinical trial
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Author / Creator
Fong, Youyi , McDermott, Adrian B. , Benkeser, David , Roels, Sanne , Stieh, Daniel J. , Vandebosch, An , Le Gars, Mathieu , Van Roey, Griet A. , Houchens, Christopher R. , Martins, Karen , Jayashankar, Lakshmi , Castellino, Flora , Amoa-Awua, Obrimpong , Basappa, Manjula , Flach, Britta , Lin, Bob C. , Moore, Christopher , Naisan, Mursal , Naqvi, Muhammed , Narpala, Sandeep , O’Connell, Sarah , Mueller, Allen , Serebryannyy, Leo , Castro, Mike , Wang, Jennifer , Petropoulos, Christos J. , Luedtke, Alex , Hyrien, Ollivier , Lu, Yiwen , Yu, Chenchen , Borate, Bhavesh , van der Laan, Lars W. P. , Hejazi, Nima S. , Kenny, Avi , Carone, Marco , Wolfe, Daniel N. , Sadoff, Jerald , Gray, Glenda E. , Grinsztejn, Beatriz , Goepfert, Paul A. , Little, Susan J. , Paiva de Sousa, Leonardo , Maboa, Rebone , Randhawa, April K. , Andrasik, Michele P. , Hendriks, Jenny , Truyers, Carla , Struyf, Frank , Schuitemaker, Hanneke , Douoguih, Macaya , Kublin, James G. , Corey, Lawrence , Neuzil, Kathleen M. , Carpp, Lindsay N. , Follmann, Dean , Gilbert, Peter B. , Koup, Richard A. , Donis, Ruben O. , and the United States Government (USG)/CoVPN Biostatistics Team , on behalf of the Immune Assays Team , the Coronavirus Vaccine Prevention Network (CoVPN)/ENSEMBLE Team , Coronavirus Vaccine Prevention Network (CoVPN)/ENSEMBLE Team and Immune Assays Team
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Measuring immune correlates of disease acquisition and protection in the context of a clinical trial is a prerequisite for improved vaccine design. We analysed binding and neutralizing antibody measurements 4 weeks post vaccination as correlates of risk of moderate to severe-critical COVID-19 through 83 d post vaccination in the phase 3, double-bli...
Alternative Titles
Full title
Immune correlates analysis of the ENSEMBLE single Ad26.COV2.S dose vaccine efficacy clinical trial
Authors, Artists and Contributors
Author / Creator
McDermott, Adrian B.
Benkeser, David
Roels, Sanne
Stieh, Daniel J.
Vandebosch, An
Le Gars, Mathieu
Van Roey, Griet A.
Houchens, Christopher R.
Martins, Karen
Jayashankar, Lakshmi
Castellino, Flora
Amoa-Awua, Obrimpong
Basappa, Manjula
Flach, Britta
Lin, Bob C.
Moore, Christopher
Naisan, Mursal
Naqvi, Muhammed
Narpala, Sandeep
O’Connell, Sarah
Mueller, Allen
Serebryannyy, Leo
Castro, Mike
Wang, Jennifer
Petropoulos, Christos J.
Luedtke, Alex
Hyrien, Ollivier
Lu, Yiwen
Yu, Chenchen
Borate, Bhavesh
van der Laan, Lars W. P.
Hejazi, Nima S.
Kenny, Avi
Carone, Marco
Wolfe, Daniel N.
Sadoff, Jerald
Gray, Glenda E.
Grinsztejn, Beatriz
Goepfert, Paul A.
Little, Susan J.
Paiva de Sousa, Leonardo
Maboa, Rebone
Randhawa, April K.
Andrasik, Michele P.
Hendriks, Jenny
Truyers, Carla
Struyf, Frank
Schuitemaker, Hanneke
Douoguih, Macaya
Kublin, James G.
Corey, Lawrence
Neuzil, Kathleen M.
Carpp, Lindsay N.
Follmann, Dean
Gilbert, Peter B.
Koup, Richard A.
Donis, Ruben O.
and the United States Government (USG)/CoVPN Biostatistics Team
on behalf of the Immune Assays Team
the Coronavirus Vaccine Prevention Network (CoVPN)/ENSEMBLE Team
Coronavirus Vaccine Prevention Network (CoVPN)/ENSEMBLE Team
Immune Assays Team
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10166187
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10166187
Other Identifiers
ISSN
2058-5276
E-ISSN
2058-5276
DOI
10.1038/s41564-022-01262-1
