Tespa1 facilitates hematopoietic and leukemic stem cell maintenance by restricting c-Myc degradation
Tespa1 facilitates hematopoietic and leukemic stem cell maintenance by restricting c-Myc degradation
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Author / Creator
Lu, Yukai , Yang, Lijing , Shen, Mingqiang , Zhang, Zihao , Wang, Song , Chen, Fang , Chen, Naicheng , Xu, Yang , Zeng, Hao , Chen, Mo , Chen, Shilei , Wang, Fengchao , Hu, Mengjia and Wang, Junping
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Hematopoietic stem cells (HSCs) and leukemia stem cells (LSCs) have robust self-renewal potential, which is responsible for sustaining normal and malignant hematopoiesis, respectively. Although considerable efforts have been made to explore the regulation of HSC and LSC maintenance, the underlying molecular mechanism remains obscure. Here, we obser...
Alternative Titles
Full title
Tespa1 facilitates hematopoietic and leukemic stem cell maintenance by restricting c-Myc degradation
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10169665
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10169665
Other Identifiers
ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/s41375-023-01880-6
