Astragalus polysaccharide ameliorates steroid-induced osteonecrosis of the femoral head by regulatin...
Astragalus polysaccharide ameliorates steroid-induced osteonecrosis of the femoral head by regulating miR-200b-3p-mediated Wnt/β-catenin signaling pathway via inhibiting SP1 expression: Astragalus polysaccharide regulates SONFH via SP1
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Publisher
England: BioMed Central
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English
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Publisher
England: BioMed Central
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Contents
Steroid-induced osteonecrosis of the femoral head (SONFH) is the necrosis of the femur bone caused by prolonged and massive use of corticosteroids. The present study probed into the significance of Astragalus polysaccharide (APS) in SONFH progression.
SONFH cell model was constructed using murine long bone osteocyte Y4 (MLO-Y4) cells and then tr...
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Full title
Astragalus polysaccharide ameliorates steroid-induced osteonecrosis of the femoral head by regulating miR-200b-3p-mediated Wnt/β-catenin signaling pathway via inhibiting SP1 expression: Astragalus polysaccharide regulates SONFH via SP1
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10170750
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10170750
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ISSN
1471-2474
E-ISSN
1471-2474
DOI
10.1186/s12891-023-06447-1
