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Effects of neprilysin and neprilysin inhibitors on glucose homeostasis: Controversial points and a p...

Effects of neprilysin and neprilysin inhibitors on glucose homeostasis: Controversial points and a p...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10172023

Effects of neprilysin and neprilysin inhibitors on glucose homeostasis: Controversial points and a promising arena

About this item

Full title

Effects of neprilysin and neprilysin inhibitors on glucose homeostasis: Controversial points and a promising arena

Publisher

Australia: John Wiley & Sons, Inc

Journal title

Journal of diabetes, 2023-05, Vol.15 (5), p.397-408

Language

English

Formats

Publication information

Publisher

Australia: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Neprilysin (NEP) is a transmembrane zinc-dependent metalloproteinase that inactivates various peptide hormones including glucagon-like peptide 1 (GLP-1). NEP inhibitors may be effective in the management of type 2 diabetes mellitus (T2DM) by increasing the circulating level of GLP-1. However, acute-effect NEP inhibitors may lead to detrimental effe...

Alternative Titles

Full title

Effects of neprilysin and neprilysin inhibitors on glucose homeostasis: Controversial points and a promising arena

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10172023

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10172023

Other Identifiers

ISSN

1753-0393

E-ISSN

1753-0407

DOI

10.1111/1753-0407.13389

How to access this item