Mendelian randomisation of eosinophils and other cell types in relation to lung function and disease
Mendelian randomisation of eosinophils and other cell types in relation to lung function and disease
About this item
Full title
Author / Creator
SpiroMeta consortium , Guyatt, Anna , John, Catherine , Williams, Alexander T , Shrine, Nick , Reeve, Nicola F , Sayers, Ian , Hall, Ian , Wain, Louise V , Sheehan, Nuala , Dudbridge, Frank , Tobin, Martin D , Cook, James P , Deary, Ian J , Enroth, Stefan , Ewert, Ralf , Gieger, Christian , Gyllensten, Ulf , Harris, Sarah E , Hayward, Caroline , Homuth, Georg , Hui, Jennie , Imboden, Medea , James, Alan L , Jarvelin, Marjo-Riitta , Joshi, Peter K , Kahonen, Mika , Karrasch, Stefan , Kentistou, Katherine A , Kerr, Shona M , Kumari, Meena , Langenberg, Claudia , Lehtimaki, Terho , Lind, Lars , Luan, Jian’an , Mahajan, Anubha , Marten, Jonathan , Morris, Andrew P , Polasek, Ozren , Porteous, David J , Probst-Hensch, Nicole M , Raitakari, Olli T , Rawal, Rajesh , Rudan, Igor , Schulz, Holger , Smith, Blair H , Strachan, David P , Stubbe, Beate , Surakka, Ida , Timmers, Paul RJH , Vitart, Véronique , Wareham, Nick , Weiss, Stefan , Wielscher, Matthias , Wilson, James F , Zeggini, Eleftheria and Zhao, Jing Hua
Publisher
England: BMJ Publishing Group Ltd and British Thoracic Society
Journal title
Language
English
Formats
Publication information
Publisher
England: BMJ Publishing Group Ltd and British Thoracic Society
Subjects
More information
Scope and Contents
Contents
RationaleEosinophils are associated with airway inflammation in respiratory disease. Eosinophil production and survival is controlled partly by interleukin-5: anti-interleukin-5 agents reduce asthma and response correlates with baseline eosinophil counts. However, whether raised eosinophils are causally related to chronic obstructive pulmonary dise...
Alternative Titles
Full title
Mendelian randomisation of eosinophils and other cell types in relation to lung function and disease
Authors, Artists and Contributors
Author / Creator
Guyatt, Anna
John, Catherine
Williams, Alexander T
Shrine, Nick
Reeve, Nicola F
Sayers, Ian
Hall, Ian
Wain, Louise V
Sheehan, Nuala
Dudbridge, Frank
Tobin, Martin D
Cook, James P
Deary, Ian J
Enroth, Stefan
Ewert, Ralf
Gieger, Christian
Gyllensten, Ulf
Harris, Sarah E
Hayward, Caroline
Homuth, Georg
Hui, Jennie
Imboden, Medea
James, Alan L
Jarvelin, Marjo-Riitta
Joshi, Peter K
Kahonen, Mika
Karrasch, Stefan
Kentistou, Katherine A
Kerr, Shona M
Kumari, Meena
Langenberg, Claudia
Lehtimaki, Terho
Lind, Lars
Luan, Jian’an
Mahajan, Anubha
Marten, Jonathan
Morris, Andrew P
Polasek, Ozren
Porteous, David J
Probst-Hensch, Nicole M
Raitakari, Olli T
Rawal, Rajesh
Rudan, Igor
Schulz, Holger
Smith, Blair H
Strachan, David P
Stubbe, Beate
Surakka, Ida
Timmers, Paul RJH
Vitart, Véronique
Wareham, Nick
Weiss, Stefan
Wielscher, Matthias
Wilson, James F
Zeggini, Eleftheria
Zhao, Jing Hua
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10176352
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10176352
Other Identifiers
ISSN
0040-6376,1468-3296
E-ISSN
1468-3296
DOI
10.1136/thoraxjnl-2021-217993
