RAF1 contributes to cell proliferation and STAT3 activation in colorectal cancer independently of mi...
RAF1 contributes to cell proliferation and STAT3 activation in colorectal cancer independently of microsatellite and KRAS status
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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More than 30% of all human cancers are driven by RAS mutations and activating KRAS mutations are present in 40% of colorectal cancer (CRC) in the two main CRC subgroups, MSS (Microsatellite Stable) and MSI (Microsatellite Instable). Studies in RAS-driven tumors have shown essential roles of the RAS effectors RAF and specifically of RAF1, which can...
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RAF1 contributes to cell proliferation and STAT3 activation in colorectal cancer independently of microsatellite and KRAS status
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10181936
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10181936
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ISSN
0950-9232,1476-5594
E-ISSN
1476-5594
DOI
10.1038/s41388-023-02683-w
