Lorlatinib with or without chemotherapy in ALK-driven refractory/relapsed neuroblastoma: phase 1 tri...
Lorlatinib with or without chemotherapy in ALK-driven refractory/relapsed neuroblastoma: phase 1 trial results
About this item
Full title
Author / Creator
Goldsmith, Kelly C. , Park, Julie R. , Kayser, Kimberly , Malvar, Jemily , Chi, Yueh-Yun , Groshen, Susan G. , Villablanca, Judith G. , Krytska, Kateryna , Lai, Lillian M. , Acharya, Patricia T. , Goodarzian, Fariba , Pawel, Bruce , Shimada, Hiroyuki , Ghazarian, Susan , States, Lisa , Marshall, Lynley , Chesler, Louis , Granger, Meaghan , Desai, Ami V. , Mody, Rajen , Morgenstern, Daniel A. , Shusterman, Suzanne , Macy, Margaret E. , Pinto, Navin , Schleiermacher, Gudrun , Vo, Kieuhoa , Thurm, Holger C. , Chen, Joseph , Liyanage, Marlon , Peltz, Gerson , Matthay, Katherine K. , Berko, Esther R. , Maris, John M. , Marachelian, Araz and Mossé, Yael P.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Neuroblastomas harbor
ALK
aberrations clinically resistant to crizotinib yet sensitive pre-clinically to the third-generation ALK inhibitor lorlatinib. We conducted a first-in-child study evaluating lorlatinib with and without chemotherapy in children and adults with relapsed or refractory ALK-driven neuroblastoma. The trial is ongoing, and w...
Alternative Titles
Full title
Lorlatinib with or without chemotherapy in ALK-driven refractory/relapsed neuroblastoma: phase 1 trial results
Authors, Artists and Contributors
Author / Creator
Park, Julie R.
Kayser, Kimberly
Malvar, Jemily
Chi, Yueh-Yun
Groshen, Susan G.
Villablanca, Judith G.
Krytska, Kateryna
Lai, Lillian M.
Acharya, Patricia T.
Goodarzian, Fariba
Pawel, Bruce
Shimada, Hiroyuki
Ghazarian, Susan
States, Lisa
Marshall, Lynley
Chesler, Louis
Granger, Meaghan
Desai, Ami V.
Mody, Rajen
Morgenstern, Daniel A.
Shusterman, Suzanne
Macy, Margaret E.
Pinto, Navin
Schleiermacher, Gudrun
Vo, Kieuhoa
Thurm, Holger C.
Chen, Joseph
Liyanage, Marlon
Peltz, Gerson
Matthay, Katherine K.
Berko, Esther R.
Maris, John M.
Marachelian, Araz
Mossé, Yael P.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10202811
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10202811
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-023-02297-5
