Proximity-Induced Nucleic Acid Degrader (PINAD) Approach to Targeted RNA Degradation Using Small Mol...
Proximity-Induced Nucleic Acid Degrader (PINAD) Approach to Targeted RNA Degradation Using Small Molecules
About this item
Full title
Author / Creator
Mikutis, Sigitas , Rebelo, Maria , Yankova, Eliza , Gu, Muxin , Tang, Cong , Coelho, Ana R. , Yang, Mo , Hazemi, Madoka E. , Pires de Miranda, Marta , Eleftheriou, Maria , Robertson, Max , Vassiliou, George S. , Adams, David J. , Simas, J. Pedro , Corzana, Francisco , Schneekloth, John S. , Tzelepis, Konstantinos and Bernardes, Gonçalo J. L.
Publisher
United States: American Chemical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Chemical Society
Subjects
More information
Scope and Contents
Contents
Nature has evolved intricate machinery to target and degrade RNA, and some of these molecular mechanisms can be adapted for therapeutic use. Small interfering RNAs and RNase H-inducing oligonucleotides have yielded therapeutic agents against diseases that cannot be tackled using protein-centered approaches. Because these therapeutic agents are nucl...
Alternative Titles
Full title
Proximity-Induced Nucleic Acid Degrader (PINAD) Approach to Targeted RNA Degradation Using Small Molecules
Authors, Artists and Contributors
Author / Creator
Rebelo, Maria
Yankova, Eliza
Gu, Muxin
Tang, Cong
Coelho, Ana R.
Yang, Mo
Hazemi, Madoka E.
Pires de Miranda, Marta
Eleftheriou, Maria
Robertson, Max
Vassiliou, George S.
Adams, David J.
Simas, J. Pedro
Corzana, Francisco
Schneekloth, John S.
Tzelepis, Konstantinos
Bernardes, Gonçalo J. L.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10214512
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10214512
Other Identifiers
ISSN
2374-7943
E-ISSN
2374-7951
DOI
10.1021/acscentsci.3c00015
