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An optimized bioluminescent substrate for non-invasive imaging in the brain

An optimized bioluminescent substrate for non-invasive imaging in the brain

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10229426

An optimized bioluminescent substrate for non-invasive imaging in the brain

About this item

Full title

An optimized bioluminescent substrate for non-invasive imaging in the brain

Publisher

New York: Nature Publishing Group US

Journal title

Nature chemical biology, 2023-06, Vol.19 (6), p.731-739

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Bioluminescence imaging (BLI) allows non-invasive visualization of cells and biochemical events in vivo and thus has become an indispensable technique in biomedical research. However, BLI in the central nervous system remains challenging because luciferases show relatively poor performance in the brain with existing substrates. Here, we report the...

Alternative Titles

Full title

An optimized bioluminescent substrate for non-invasive imaging in the brain

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10229426

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10229426

Other Identifiers

ISSN

1552-4450

E-ISSN

1552-4469

DOI

10.1038/s41589-023-01265-x

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