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Anaplastic transformation in thyroid cancer revealed by single-cell transcriptomics

Anaplastic transformation in thyroid cancer revealed by single-cell transcriptomics

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10231997

Anaplastic transformation in thyroid cancer revealed by single-cell transcriptomics

About this item

Full title

Anaplastic transformation in thyroid cancer revealed by single-cell transcriptomics

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2023-06, Vol.133 (11), p.1-18

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

The deadliest anaplastic thyroid cancer (ATC) often transforms from indolent differentiated thyroid cancer (DTC); however, the complex intratumor transformation process is poorly understood. We investigated an anaplastic transformation model by dissecting both cell lineage and cell fate transitions using single-cell transcriptomic and genetic alter...

Alternative Titles

Full title

Anaplastic transformation in thyroid cancer revealed by single-cell transcriptomics

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10231997

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10231997

Other Identifiers

ISSN

1558-8238,0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI169653

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